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What is Epigenetic Orthodontics?
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Q: What is Epigenetic Orthodontics?
A: Epigenetic orthodontics uses a personís natural genes to correct and straighten the teeth without the use of force brackets.
Click here to see the video-interview with Dental Economics
Click here to listen to an Interview with the Australian Dental Association

Q: Are genes involved in the treatments in any way?
A: Yes,in the sense that the human genome is implicated during orthodontic/orthopedic/pneumopedic™ (non-surgical airway remodeling™) airway treatments, and that certain devices or appliances,such as the (Daytime-Nighttime Appliance™ DNA appliance™) can upregulate or modulate gene expression during orthodontic/orthopedic/pneumopedic™ (non-surgical airway remodeling™)airway treatments. However, no artificial genes or gene-transfer is used at all. Only the patient's naturally-occurring genes are implicated in Dr Singh's Epigenetic orthodontic concept. In other words, new, orthodontic/orthopedic/pneumopedic™devices or DNA appliances™ are involved in a system that has been specially-designed by Dr Singh to bioengineer craniofacial, dental, and airway structures so that natural developmental processes are evoked by Dr Singh's orthodontic/orthopedic/pneumopedic™ devices or DNA appliances™ to enhance the teeth, jaws, TMJ, face and airway into more optimal relations for functions, such as sleep and breathing.

Q: How does Epigenetic Orthodontics work?
A: Dr Singh believes that by changing the spatial relations of crooked teeth, using a new generation of orthodontic-orthopedic-pneumopedic™ DNA appliances™ , which can be worn similar to removable orthodontic retainers, the various genes that control tooth position will be activated so that orthodontists and dentists can enhance dental and oral health, including non-surgical airway remodeling™ . Some evidence for these ideas is already available in the dental, orthodontic and medical literature. These new DNA appliances™ rely less on the continuous force exerted by conventional orthodontic braces, but help to guide the teeth, jaws, TMJ, face and airway into more optimal relations for functions, such as sleep and breathing. Specifically, these new DNA appliances™ consist of 3-D Axial springs™ that are specially made from Do-Not-Adjust wire™ or DNA wire™ which, as its name suggests, requires virtually little or no adjustment by the dental professional.

Q: What does Epigenetic Orthodontics mean?
A: Epigenetic orthodontics means that various human genes or combinations of the patient's naturally-inherited genes are harnessed in combination or independently with various orthodontic/orthopedic/pneumopedic™ devices or DNA appliances™ to modify, change or attenuate the physical location of natural teeth, jaws and airway in 3-D space during orthodontic/orthopedic/pneumopedic™ treatments, based on the concept of 'temporo-spatial patterning.' The term "temporo-spatial patterning" like Global Positioning Satellite (GPS) implies that the spatial organization of the teeth, jaws and airway can be mapped in 3-D space at known anatomical locations using x, y, z coordinates. The pattern in 3-D space of craniofacial structures are encoded within the patient's genome. Dr Singh believes that DNA appliances™ are capable of modulating genetic pathways, which are effectively dormant or inactive, and are capable of restarting craniofacial development in adult patients as well as in children. In addition, abnormal patterning is corrected, in part, through the deployment of orthodontic/orthopedic/pneumopedic™ devices or DNA appliances™ , which may evoke natural developmental processes that improve a patient's airway and thereby ameliorate or prevent airway issues such as snoring and other forms of sleep-disordered breathing through non-surgical airway remodeling™ .

Q: What makes Epigenetic Orthodontics different?
A: Traditionally, specially-trained orthodontists use fixed braces to apply forces to straighten crooked teeth. While many of these cases are initially treated successfully, few patients know that relapse can occur after treatment. Relapse means that a patient's teeth will move back after treatment has been completed. The reasons for relapse are complex and remain incompletely understood. However, the entire human genome has now been sequenced, and we now know that certain genes are involved in moving teeth. Teeth are naturally-designed to move, for example, tooth eruption in a normally-growing child. In addition, the teeth in some people erupt in a specific arrangement, producing a beautiful smile. Dr Singh believes that the specific arrangement of teeth is due to certain genes. In fact, a natural process called 'temporo-spatial patterning' is at work. This process is the blueprint or body plan that is encoded by genes. In other words, the right and left sides of the body, the top and bottom of the body as well as the front and back of the entire body is under the control of a genetic body plan, including the teeth. Sometimes, however, the plan gets disturbed, producing crooked teeth, for example. The Daytime-Nighttime Appliance™ system uses DNA appliances™ to address these issues.
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